Online Catalog
A collection of nonclinical studies & assays; customization is possible.

Model: Humanized oncology

Models (Disease)

Pharmacology (Safety)

Humanized oncology mouse models are established by the transplantation of human peripheral blood mononuclear cells (PBMCs) or hematopoietic stem cells (HSCs) into severely immunocompromised NSG mice, harboring tumors established from human cancer cell lines or human patient-derived xenografts (PDX) material. 

These models can then be used to screen immunotherapy agents against cancers and to explore the potential combinations of these agents to treat patients and predict outcomes.

Molecule or Product Type

Small Molecule

Models

Human, Mouse

Administration Routes

Dermal, Dietary, Gavage, Implant, Intramuscular, Intraperitoneal, Intravenous, Subcutaneous

Phase

Discovery

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About our nonclinical animal research models: We provide the utmost care for our research animals and actively pursue advances in animal welfare. As well as ensuring the highest scientific, ethical and regulatory standards, selection of appropriate animal research models for development research is critical to developing safe and effective treatments, devices and products that protect and save lives. Just as we have ethical committee oversight for human trials, we have ethical committees overseeing all aspects of our global animal care and use programs. All of our core, nonclinical facilities are accredited by AAALAC. Learn more about our commitment to replacing, reusing and refining nonclinical research models.

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Labcorp is a leading global life sciences company that includes contract research and developmental services to the pharmaceutical, medical technology, crop protection and chemical industries.

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